Publications

2024

Honghui Lee, Shihwa Seong, Eun Seo Bae, Seung Hyun Choi, Jinwoo Lee, Seok Beom Lee, Dong-Chan Oh, Sang Kook Lee and Suckchang Hong*

"Total synthesis of Deinococcucins A-D and their isomeric derivatives via stereo- and regio-selective glycosylation: the discovery of a novel anti-angiogenic agent" Org. Chem. Front., 2024,

Eun Seo Bae, Junhwa Hong, Yijae Lim, Woong Sub Byun, Simin Chun, Suckchang Hong*, and Sang Kook Lee*

"Evo312: An Evodiamine Analog and Novel PKCβI Inhibitor with Potent Antitumor Activity in Gemcitabine-Resistant Pancreatic Cancer" J. Med. Chem. 2024, 67, 17, 14885–14911

2023

Simin Chun, Ramachandra Reddy Putta, Junhwa Hong, Seung Hyun Choi, Dong-Chan Oh, and Suckchang Hong*

"Iron-Catalyzed Transfer Hydrogenation: Divergent Synthesis of Quinolines and Quinolones from ortho-Nitrobenzyl Alcohols" Adv. Synth. Catal. 2023, 365, 3367–3374.

Seok Beom Lee, Simin Chun, Seung Hyun Choi, Junhwa Hong, Dong-Chan Oh, and Suckchang Hong*

"Iron-Catalyzed Oxidative Cyclization of 2-Amino Styrenes with Alcohols and Methyl Arenes for the Synthesis of Polysubstituted Quinolines" J. Org. Chem. 2023, 88, 13, 8099–8113.

Woong Sub Byun, Hyewon Lim, Junhwa Hong, Eun Seo Bae, Seok Beom Lee, Younggwan Kim, Jeeyeon Lee, Sang Kook Lee*, and Suckchang Hong*

"Design, Synthesis, and Biological Activity of Marinacarboline Analogues as STAT3 Pathway Inhibitors for Docetaxel-Resistant Triple-Negative Breast Cancer" J. Med. Chem. 2023, 66, 4, 3106–3133.

Yern-Hyerk Shin, Ji Hyeon Im, Ilnam Kang, Eunji Kim, Sung Chul Jang, Eunji Cho, Daniel Shin, Sunghoon Hwang, Young Eun Du, Thanh-Hau Huynh, Keebeom Ko, Yoon-Joo Ko, Sang-Jip Nam, Takayoshi Awakawa, Jeeyeon Lee, Suckchang Hong, Ikuro Abe, Bradley S. Moore, William Fenical, Yeo Joon Yoon, Jang-Cheon Cho, Sang Kook Lee, Ki-Bong Oh, and Dong-Chan Oh*

"Genomic and Spectroscopic Signature-Based Discovery of Natural Macrolactams" J. Am. Chem. Soc. 2023, 145, 3, 1886–1896.

Hye-Young Min, Yijae Lim, Hyukjin Kwon, Hye-Jin Boo, Seung Yeob Hyun, Junhwa Hong, Suckchang Hong, and Ho-Young Lee*

"An A-ring substituted evodiamine derivative with potent anticancer activity against human non-small cell lung cancer cells by targeting heat shock protein 70" Biochemical Pharmacology 2023, 211, 115507.

Daniel Shin, Woong Sub Byun, Sangwook Kang, Ilnam Kang, Eun Seo Bae, Joon Soo An, Ji Hyeon Im, Jiyoon Park, Eunji Kim, Keebeom Ko, Sunghoon Hwang, Honghui Lee, Yun Kwon, Yoon-Joo Ko, Suckchang Hong, Sang-Jip Nam, Seung Bum Kim, William Fenical, Yeo Joon Yoon, Jang-Cheon Cho, Sang Kook Lee*, and Dong-Chan Oh*

"Targeted and Logical Discovery of Piperazic Acid-Bearing Natural Products Based on Genomic and Spectroscopic Signatures" J. Am. Chem. Soc. 2023, 145, 36, 19676–19690.

2022

Ramachandra Reddy Putta, Simin Chun, Seok Beom Lee, Junhwa Hong, Seung Hyun Choi, Dong-Chan Oh, and Suckchang Hong*

"Chemoselective α-Alkylation and α-Olefination of Arylacetonitriles with Alcohols via Iron-Catalyzed Borrowing Hydrogen and Dehydrogenative Coupling" J. Org. Chem. 2022, 87, 24, 16378–16389.

Joonseok Jang, Jinwoo Lee, Seok Beom Lee, Seung Hyun Choi, Eun Jin Park, Sang Jun Yoon, Joon Soo An, Dong-Chan Oh, Won Keun Oh, and Suckchang Hong*

"Total Synthesis of Melicoptelines C–E: Antiviral Cyclopeptides Containing a Hexahydropyrrolo[2,3-b]indole Moiety" Org. Lett. 2022, 24, 32, 6043–6048.

Geumwoo Lee, Jeong-Hee Lee, Jaeyong Lee, Min Woo Ha, Mi-hyun Kim, Suckchang Hong, and Hyeung-geun Park*

"Asymmetric epoxidation of enones: effect of surfactants, radical scavengers and morphology of catalysts on reaction rates, chemical yields and enantioselectivities in phase-transfer catalysis" Org. Chem. Front., 2022, 9, 4902-4909.

Jaeyong Lee, Jeong Woo Ban, Jeongseok Kim, Sehun Yang, Geumwoo Lee, Lama Prema Dhorma, Mi-hyun Kim, Min Woo Ha, Suckchang Hong, and Hyeung-geun Park*

"Asymmetric Phase-Transfer Catalytic aza-Michael Addition to Cyclic Enone: Highly Enantioselective and Diastereoselective Synthesis of Cyclic 1,3-Aminoalcohols" Org. Lett. 2022, 24, 8, 1647–1651.

2021

Jiwon Ahn, Seok Beom Lee, Injae Song, Simin Chun, Dong-Chan Oh, and Suckchang Hong*

"Synthesis of 4-Aryl Pyrrolo[1,2-α]quinoxalines via Iron-Catalyzed Oxidative Coupling from an Unactivated Methyl Arene" The Journal of Organic Chemistry 2021. 86, 11, 7390–7402.

Ramachandra Reddy Putta, Simin Chun, Seok Beom Lee, Junhwa Hong, Dong-Chan Oh, and Suckchang Hong*

"Iron-catalyzed one-pot synthesis of quinoxalines: transfer hydrogenative condensation of 2-nitroanilines with vicinal diols" RSC Advances 2021, 11, 30, 18225-18230.

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Injae Song, Hyewon Lim, Simin Chun, Seok Beom Lee, Jungmoo Huh, Dong-Chan Oh, and Suckchang Hong*

"First Total Synthesis of Gaylussacin and Its Stilbene Derivatives" J. Nat. Prod. 2021, 84, 4, 1366–1372

Seung Yeob Hyun, Huong Thuy Le, Hye-Young Min, Honglan Pei, Yijae Lim, Injae Song, Yen T. K. Nguyen, Suckchang Hong, Byung Woo Han, Ho-Young Lee*

"Evodiamine inhibits both stem cell and non-stem-cell populations in human cancer cells by targeting heat shock protein 70" Theranostics 2021, 11(6), 2932-2952.

Myoun-Su Kim, Munhyung Bae,Ye-Eun Jung,Jung Min Kim, Sunghoon Hwang, Myoung Chong Song, Yeon Hee Ban, Eun Seo Bae, Suckchang Hong, Sang Kook Lee, Sun-Shin Cha*, Dong-Chan Oh*, Yeo Joon Yoon*

"Unprecedented Noncanonical Features of the Nonlinear Nonribosomal Peptide Synthetase Assembly Line for WS9326A Biosynthesis" Angewandte Chemie International Edition 2021, 60(36), 19766-19773.

Joon Soo An, Bora Shin, Tae Ho Kim, Sunghoon Hwang, Yern-Hyerk Shin, Jinsheng Cui, Young Eun Du, Jungwoo Yi, Sang-Jip Nam, Suckchang Hong, Jongheon Shin, Jichan Jang, Yeo Joon Yoon, and Dong-Chan Oh*

"Dumulmycin, an Antitubercular Bicyclic Macrolide from a Riverine Sediment-Derived Streptomyces sp." Org. Lett. 2021, 23, 9, 3359–3363.

Jewon Yang, Yohan Park, Sehun Yang, Geumwoo Lee, Min Woo Ha, Mi-hyun Kim, Suckchang Hong, and Hyeung-geun Park*

"Enantioselective Total Synthesis of Nitraria Alkaloids: (+)-Nitramine, (+)-Isonitramine, (−)-Isonitramine, and (−)-Sibirine via Asymmetric Phase-Transfer Catalytic α-Allylations of α-Carboxylactams" J. Org. Chem. 2021, 86, 6, 4375–4390.

2020

Ramachandra Reddy Putta, Simin Chun, Seung Hyun Choi, Seok Beom Lee, Dong-Chan Oh, and Suckchang Hong*

"Iron(0)-Catalyzed Transfer Hydrogenative Condensation of Nitroarenes with Alcohols: A Straightforward Approach to Benzoxazoles, Benzothiazoles, and Benzimidazoles" J. Org. Chem. 2020, 85, 15396−15405

Simin Chun, Jiwon Ahn, Ramachandra Reddy Putta, Seok Beom Lee, Dong-Chan Oh, and Suckchang Hong*

"Direct Synthesis of Pyrrolo[1,2-α]quinoxalines via Iron-Catalyzed Transfer Hydrogenation between 1-(2-Nitrophenyl)pyrroles and Alcohols" J. Org. Chem. 2020, 85, 15314−15324

Seok Beom Lee, Yoonkyung Jang, Jiwon Ahn, Simin Chun, Dong-Chan Oh, and Suckchang Hong*

"One-Pot Synthesis of 4‑Quinolone via Iron-Catalyzed Oxidative Coupling of Alcohol and Methyl Arene" Org. Lett. 2020, 22, 8382−8386

Saegun Kim, Daeun Jeoung, Kunyoung Kim, Seok Beom Lee, Suk Hun Lee, Min Seo Park, Prithwish Ghosh, Neeraj Kumar Mishra, Suckchang Hong,* and In Su Kim*

"Site‐Selective C–H Amidation of 2‐Aryl Quinazolinones Using Nitrene Surrogates" Eur. J. Org. Chem. 2020, 7134–7143

Ramachandra Reddy Putta, Simin Chun, Seok Beom Lee, Dong-Chan Oh, and Suckchang Hong*

"Iron-Catalyzed Acceptorless Dehydrogenative Coupling of Alcohols With Aromatic Diamines: Selective Synthesis of 1,2-Disubstituted Benzimidazoles" Front. Chem. 8:429.

Yoonkyung Jang, Seok Beom Lee, Junhwa Hong, Simin Chun, Jeeyeon Lee and Suckchang Hong*

"Synthesis of 2-aryl quinazolinones via iron-catalyzed cross-dehydrogenative coupling (CDC) between N–H and C–H bonds" Org. Biomol. Chem. 2020, 18, 5435–5441

Young Eun Du, Woong Sub Byun, Seok Beom Lee, Sunghoon Hwang, Yern-Hyerk Shin, Bora Shin, Yong-Joon Jang, Suckchang Hong, Jongheon Shin, Sang Kook Lee, and Dong-Chan Oh*

"Formicins, N-Acetylcysteamine-Bearing Indenone Thioesters from a Wood Ant-Associated Bacterium" Org. Lett. 2020, 22, 5337−5341

Sunghoon Hwang, Daniel Shin, Tae Ho Kim, Joon Soo An, Shin-Il Jo, Jichan Jang, Suckchang Hong, Jongheon Shin, and Dong-Chan Oh*

"Structural Revision of Lydiamycin A by Reinvestigation of the Stereochemistry” Org. Lett. 2020, 22, 3855−3859

Yern-Hyerk Shin, Saeyeon Kang, Woong Sub Byun, Chang-Wook Jeon, Beomkoo Chung, Ji Yoon Beom, Suckchang Hong, Jeeyeon Lee, Jongheon Shin, Youn-Sig Kwak, Sang Kook Lee, Ki-Bong Oh, Yeo Joon Yoon, and Dong-Chan Oh*

"Absolute Configuration and Antibiotic Activity of Piceamycin" J. Nat. Prod. 2020, 83, 277−285

Yeonghun Jung, Jee Eun Hong, Seung Tae Baek, Suckchang Hong, Jae-Hwan Kwak, and Yohan Park*

"4-Dimethylaminopyridine-Catalyzed Metal-Free Aerobic Oxidation of Aryl α-Halo Esters to Aryl α-Keto Esters" ACS Omega 2020, 5, 36, 22951–22957.

So Hyun Jung, Byungsoo Kim, Cheonhyoung Park, Jeongseok Kim, Min Woo Ha, Suckchang Hong, Hyeung-geun Park*

"Enantioselective Synthesis of Chiral α-Alkylthiomalonates via a Phase-Transfer-Catalyzed α-Sulfenylation of α-Alkylmalonates" Asian J. Org. Chem. 2019, 8, 1-9

Bumhee Lim,1, Byungyeob Baek,1, Kyungkuk Jang, Na Keum Lee, Ji Hye Lee, Yeongcheol Lee, Jinwoo Kim, San Won Kang, Jaehyun Park, Suzi Kim, Nae-Won Kang, Suckchang Hong, Dae-Duk Kim, Ikyon Kim, Hyonseok Hwang, Jeeyeon Lee*

"Novel turn-on ﬂuorescent biosensors for selective detection of cellular Fe3+ in lysosomes: Thiophene as a selectivity-tuning handle for Fe3+ sensors” Dyes and Pigments 2019, 169, 51–59

2019

2018

Min Woo Ha, Jun Young Lee, Doyoung Kim, Geumwoo Lee, Jae Kyun Lee, Suckchang Hong, and Hyeung-geun Park*

"Enantioselective Synthesis of Chiral α‑Thio-Quaternary Stereogenic Centers via Phase-Transfer-Catalyzed α‑Alkylation of α‑Acylthiomalonates" J. Org. Chem. 2018, 83, 1011−1018

2017

Doyoung Kim, Min Woo Ha, Suckchang Hong, Cheonhyoung Park, Byungsoo Kim, Jewon Yang, and Hyeung-geun Park*

"Enantioselective Synthesis of Chiral α‑Azido and α‑Aryloxy Quaternary Stereogenic Centers via the Phase-Transfer-Catalyzed α‑Alkylation of α-Bromomalonates, Followed by SN2 Substitutio" J. Org. Chem. 2017, 82, 4936−4943

2016

Inji Shin, Suckchang Hong, Michael J. Krische.*

"Total Synthesis of Swinholide A: An Exposition in Hydrogen-Mediated C-C Bond Formation” Journal of the American Chemical Society 2016, 138(43), 14246-14249.

Min Woo Ha, Sujee Choi, Seek Kim, Jun Young Lee, Jae Kyun Lee, Jeeyeon Lee, Suckchang Hong,* Hyeung-geun Park.*

"Phase-transfer catalyzed enantioselective α-alkylation of α-acyloxymalonates: construction of chiral α-hydroxy quaternary stereogenic centers” RCS Advances 2016, 6(81), 77427-77430.

Suckchang Hong, Michael J. Krische.

"Beyond Protecting Groups in Metal Catalyzed C-C Coupling: Direct Anomeric Propargylation of Aldoses” ACS Central Science 2016, 2(1), 12-13.

2015

Ryosuke Tsutsumi, Suckchang Hong, Michael J. Krische.*

"Diastereo- and Enantioselective Iridium Catalyzed Carbonyl (α-Cyclopropyl)allylation via Transfer Hydrogenation” Chemistry - A European Journal 2015, 21(37), 12903-12907.

Min Woo Ha, Myungmo Lee, Sujee Choi, Seek Kim, Suckchang Hong, Yohan Park, Mi-hyun Kim, Taek-Soo Kim, Jihoon Lee, Jae Kyun Lee, Hyeung-geun Park.*

"Construction of Chiral α-Amino Quaternary Stereogenic Centers via Phase-Transfer Catalyzed Enantioselective α-Alkylation of α-Amidomalonates” Journal of Organic Chemistry 2015, 80(6), 3270-3279.

Suckchang Hong, Yoonho Shin, Myunggi Jung, Min Woo Ha, Yohan Park, Yeon-Ju Lee, Jongheon Shin, Ki Bong Oh, Sang Kook Lee,* Hyeung-geun Park.*

"Efficient synthesis and biological activity of Psammaplin A and its analogues as antitumor agents” European Journal of Medicinal Chemistry 2015, 96, 218-230.

Cheonhyoung Park, Min Woo Ha, Byungsoo Kim, Suckchang Hong, Doyoung Kim, Yohan Park, Mi-hyun Kim, Jae Kyun Lee, Jeeyeon Lee, Hyeung-geun Park.*

"Enantioselective α-Alkylation of Benzylideneamino tert-Butyl Malonates by Phase-Transfer Catalysis” Advanced Synthesis & Catalysis 2015, 357(13), 2841-2848.

2014

Yong-Hyun Han, Hyeon-Ji Kim, Eun-Jin Kim, Kyu-Seo Kim, Suckchang Hong, Hyeung-Geun Park, Mi-Ock Lee.

"RORα Decreases Oxidative Stress Through the Induction of SOD2 and GPx1 Expression and Thereby Protects Against Nonalcoholic Steatohepatitis in Mice” Antioxidants & Redox Signaling 2014, 21(15), 2083-2094.

Hwanhyuk Lee, Su Jung Hwang, Jisung Jung, Suckchang Hong, Myungmo Lee, Hyeung-geun Park, Hyo-Jong Lee, Yohan Park.

"Asymmetric synthesis and evaluation of α-quaternary chiral lactam derivatives as novel anticancer agents” Archives of Pharmacal Research 2014, 37(10), 1264-1270.

Suckchang Hong, Minsik Kim, Myunggi Jung, Min Woo Ha, Myungmo Lee, Yohan Park, Mi-hyun Kim, Taek-Soo Kim, Jihoon Lee, Hyeung-geun Park.

"Enantioselective synthesis of α-halo-α-alkylmalonates via phase-transfer catalytic α-alkylation” Organic & Biomolecular Chemistry 2014, 12(9), 1510-1517.

Jisung Jung, Suryeon Park, Suckchang Hong, Min Woo Ha, Hyeung-geun Park, Youmie Park, Hyo-Jong Lee, Yohan Park.

"Synthesis of gold nanoparticles with glycosides: synthetic trends based on the structures of glycones and aglycones” Carbohydrate Research 2014, 386, 57-61.

2013

Suckchang Hong, Myunggi Jung, Yohan Park, Min Woo Ha, Cheonhyoung Park, Myungmo Lee, Hyeung-geun Park*.

"Efficient Enantioselective Total Synthesis of (-)-Horsfiline” Chemistry - A European Journal 2013, 19(29), 9599-9605. July 15.

Min Woo Ha, Suckchang Hong, Cheonhyoung Park, Yohan Park, Jihye Lee, Mi-hyun Kim, Jihoon Lee, Hyeung-geun Park*.

"Enantioselective phase-transfer catalytic α-alkylation of 2-methylbenzyl tert-butyl malonates” Organic & Biomolecular Chemistry 2013, 11(24), 4030-4039.

Myungmo Lee, Young-Ju Lee, Eunyoung Park, Yohan Park, Min Woo Ha, Suckchang Hong, Yeon-Ju Lee, Taek-Soo Kim, Mi-hyun Kim, Hyeung-geun Park*.

"Highly enantioselective synthesis of 5-phenyl-2-alkylprolines using phase-transfer catalytic alkylation” Organic & Biomolecular Chemistry 2013, 11(12), 2039-2046.

Min Woo Ha, Heejin Lee, Hye Yeong Yi, Yohan Park, Sori Kim, Suckchang Hong, Myungmo Lee, Mi-hyun Kim, Taek-Soo Kim, Hyeung-geun Park*.

"Enantioselective Phase-Transfer Catalytic α-Benzylation and α-Allylation of α-tert-Butoxycarbonyllactones” Advanced Synthesis & Catalysis 2013, 355(4), 637-642.

2012

Yohan Park, Suckchang Hong, Myungmo Lee, Hyojun Jung, Won-Jea Cho, Eun-Jin Kim, Ho-Young Son, Mi-Ock Lee, Hyeung-geun Park*.

"N-methylthioureas as new agonists of retinoic acid receptor-related orphan receptor” Archives of Pharmacal Research 2012, 35(8), 1393-1401.

Suckchang Hong, Myungmo Lee, Myunggi Jung, Yohan Park, Mi-hyun Kim, Hyeung-geun Park*.

"Efficient synthetic method of psammaplin A” Tetrahedron Letters 2012, 53(32), 4209-4211.

Eun-Jin Kim, Young-Sil Yoon, Suckchang Hong, Ho-Young Son, Tae-Young Na, Min-Ho Lee, Hyun-Jin Kang, Jinyoung Park, Won-Jea Cho, Sang-Gun Kim, Seung-Hoi Koo, Hyeung-geun Park, Mi-Ock Lee*.

"Retinoic acid receptor-related orphan receptor α-induced activation of adenosine monophosphate-activated protein kinase results in attenuation of hepatic steatosis” Hepatology (Hoboken, NJ, United States) 2012, 55(5), 1379-1388.

Yohan Park, Young Ju Lee, Suckchang Hong, Myungmo Lee, Hyeung-geun Park*.

"Highly Enantioselective Total Synthesis of (+)-Isonitramine” Organic Letters 2012, 14(3), 852-854.

2011

Yohan Park, Young Ju Lee, Suckchang Hong, Mi-hyun Kim, Myungmo Lee, Taek-Soo Kim, Jae Kyun Lee, Sang-sup Jew, Hyeung-geun Park*.

"Highly Enantioselective Phase-Transfer Catalytic α-Alkylation of α-tert-Butoxycarbonyllactams: Construction of β-Quaternary Chiral Pyrrolidine and Piperidine Systems” Advanced Synthesis & Catalysis 2011, 353(18), 3313-3318.

Suckchang Hong, Jihye Lee, Minsik Kim, Yohan Park, Cheonhyoung Park, Mi-hyun Kim, Sang-sup Jew, Hyeung-geun Park*.

"Highly Enantioselective Synthesis of α,α-Dialkylmalonates by Phase-Transfer Catalytic Desymmetrization” Journal of the American Chemical Society 2011, 133(13), 4924-4929.